CAS RN 71203-35-5
IUPAC Navn:
4-[5-(4-methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl]benzene-1-sulfonamide
Synonymer:
4-[5-(4-methoxyphenyl)-3-phenyl-4,5-dihydropyrazol-1-yl]benzenesulfonamide
Molekylvægt (g/mol):
407.49
Molekylformel:
C22H21N3O3S
InChi Key:
QBNZBMVRFYREHK-UHFFFAOYNA-N
SMILES:
COC1=CC=C(C=C1)C1CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C1=CC=CC=C1
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Resultater
1
Tocris Bioscience™ ML 141
CAS: 71203-35-5 Molekylær formel: C22H21N3O3S
2
ML141, MedChemExpress
MedChemExpress ML141 (CID-2950007) is a potent, allosteric, selective and reversible non-competitive inhibitor of Cdc42 GTPase. ML141 inhibits Cdc42 wild type and Cdc42 Q61L mutant with EC50s of 2.1 and 2.6 μM, respectively. ML141 shows low micromolar potency and selectivity against other members of the Rho family of GTPases (Rac1, Rab2, Rab7). ML141 do not show cytotoxicity in multiple cell lines.
