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ML141, MedChemExpress

Artikelnummer. 16485318
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Mængde:
5 mg
10 mg
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Pakningsstørrelse:
50mg
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Artikelnummer. 16485318 Leverandør Medchem Express Leverandørnr. HY12755

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Beskrivelse

MedChemExpress ML141 (CID-2950007) is a potent, allosteric, selective and reversible non-competitive inhibitor of Cdc42 GTPase. ML141 inhibits Cdc42 wild type and Cdc42 Q61L mutant with EC50s of 2.1 and 2.6 μM, respectively. ML141 shows low micromolar potency and selectivity against other members of the Rho family of GTPases (Rac1, Rab2, Rab7). ML141 do not show cytotoxicity in multiple cell lines.

ML141 (CID-2950007) is a potent, allosteric, selective and reversible non-competitive inhibitor of Cdc42 GTPase. ML141 inhibits Cdc42 wild type and Cdc42 Q61L mutant with EC50s of 2.1 and 2.6 μM, respectively. ML141 shows low micromolar potency and selectivity against other members of the Rho family of GTPases (Rac1, Rab2, Rab7). ML141 do not show cytotoxicity in multiple cell lines.

Tekniske data

Kemisk navn eller materiale ML141
CAS 71203-35-5
Farve Off-White
Renhedsgrad noter Research
Molekylær formel C22H21N3O3S
Mængde 10 mg
Synonym CID-2950007
Opløselighedsinformation DMSO : ≥ 55 mg/mL (134.97 mM)
SMIL O=S(C1=CC=C(N2N=C(C3=CC=CC=C3)CC2C4=CC=C(OC)C=C4)C=C1)(N)=O
Molekylvægt (g/mol) 407.49
Formel vægt 407.49
Procent renhed 98.03%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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