CAS RN 675576-97-3

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MedChemExpress Nutlin-3b is a p53/MDM2 inhibitor with an IC50 of 13.6 μM. Nutlin-3b is 150 times less potent in binding to MDM2 than Nutlin-3a.

Kemisk navn eller materiale	Nutlin-3b
Formel vægt	581.49
Opløselighedsinformation	DMSO : ≥ 100 mg/mL (171.97 mM)
Procent renhed	98.0%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	581.49
CAS	675576-97-3
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C1NCCN(C(N2[C@@H](C3=CC=C(Cl)C=C3)[C@@H](C4=CC=C(Cl)C=C4)N=C2C5=CC=C(OC)C=C5OC(C)C)=O)C1
Renhedsgrad noter	Research
Molekylær formel	C₃₀H₃₀Cl₂N₄O₄
Til brug med (applikation)	Cancer-programmed cell death