CAS RN 58880-19-6

IUPAC Navn: (2E,4E)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide

Synonymer: trichostatin A

Molekylvægt (g/mol): 302.37

Molekylformel: C17H22N2O3

InChi Key: RTKIYFITIVXBLE-WKWSCTOINA-N

SMILES: CC(\C=C(/C)\C=C\C(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C

1 – 3 af 3 Resultater

Epigenetic modifier; Inhibits histone deacetylase (HDAC)1 and HDAC6

MedChemExpress Trichostatin A (TSA) is a potent and specific inhibitor of HDAC class I/II, with an IC50 value of 1.8 nM for HDAC.

Kemisk navn eller materiale	Trichostatin A
Sundhedsfare 1	H302+H312+H332∣H315∣H317∣H319∣H335
Formel vægt	302.37
Opløselighedsinformation	DMSO : 25 mg/mL (82.68 mM; Need ultrasonic)
Procent renhed	95.0%
Fysisk form	Solid
Farve	Light Nude
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	302.37
CAS	58880-19-6
Synonym	TSA
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	CN(C1=CC=C(C=C1)C([C@@H](/C=C(/C=C/C(NO)=O)C)C)=O)C
Renhedsgrad noter	Research
Molekylær formel	C₁₇H₂₂N₂O₃
Til brug med (applikation)	Cancer-programmed cell death