CAS RN 518303-20-3

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MedChemExpress UMI-77 is a selective Mcl-1 inhibitor, which shows high binding affinity to Mcl-1 (IC50=0.31 μM). UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2 members.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	UMI-77
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	468.34
Opløselighedsinformation	DMSO : ≥ 28 mg/mL (59.79 mM)
Procent renhed	95.0%
Fysisk form	Powder
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	468.34
CAS	518303-20-3
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(O)CSC1=CC(NS(=O)(C2=CC=C(Br)C=C2)=O)=C3C=CC=CC3=C1O
Renhedsgrad noter	Research
Molekylær formel	C₁₈H₁₄BrNO₅S₂
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 518303-20-3

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