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CAS RN 500287-72-9

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1

Rilpivirine, TRC

CAS: 500287-72-9 Molekylær formel: C22 H18 N6 Molekylvægt (g/mol): 366.42 Synonym: 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile,Edurant,R 278474,Rilpivirine,TMC 278 IUPAC navn: 4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-dimethylanilino]pyrimidin-2-yl]amino]benzonitrile SMIL: Cc1cc(\C=C\C#N)cc(C)c1Nc2ccnc(Nc3ccc(cc3)C#N)n2

Molekylvægt (g/mol) 366.42
CAS 500287-72-9
Synonym 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile,Edurant,R 278474,Rilpivirine,TMC 278
SMIL Cc1cc(\C=C\C#N)cc(C)c1Nc2ccnc(Nc3ccc(cc3)C#N)n2
IUPAC navn 4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-dimethylanilino]pyrimidin-2-yl]amino]benzonitrile
Molekylær formel C22 H18 N6
2

Tocris Bioscience™ Rilpivirine
GREENER_CHOICE

Non-nucleoside reverse transcriptase inhibitor

Kemisk navn eller materiale 4-[[4-[[4-[(1 E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
Anbefalet opbevaring Store at -20°C
CAS 500287-72-9
Mål RNA/DNA Polymerase Inhibitors
Renhed 0.98
Molekylær formel C22H18N6
3

Rilpivirine, MedChemExpress

MedChemExpress Rilpivirine (R278474) is a potent and specific diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). Rilpivirine has high antiviral activity against wild-type HIV (EC50=0.4 nM) and mutant viruses (EC50=0.1-2.0 nM). Rilpivirine has a high genetic barrier to resistance development of HIV.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Rilpivirine
Sundhedsfare 1 H302
Formel vægt 366.42
Opløselighedsinformation DMSO : 50 mg/mL (136.46 mM; Need ultrasonic)
Procent renhed 98.0%
Fysisk form Solid
Farve Yellow
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 366.42
CAS 500287-72-9
Synonym R278474 TMC278 DB08864
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL CC1=CC(/C=C/C#N)=CC(C)=C1NC2=CC=NC(NC3=CC=C(C=C3)C#N)=N2
Renhedsgrad noter Research
Molekylær formel C22H18N6
Til brug med (applikation) COVID-19-anti-virus