CAS RN 473719-41-4

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AMG 487, MedChemExpress

MedChemExpress AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	AMG 487
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	603.59
Opløselighedsinformation	DMSO : ≥ 41 mg/mL (67.93 mM)
Procent renhed	99.17%
Fysisk form	Solid
Farve	Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	603.59
CAS	473719-41-4
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(N([C@@H](C1=NC2=NC=CC=C2C(N1C3=CC=C(OCC)C=C3)=O)C)CC4=CC=CN=C4)CC5=CC=C(OC(F)(F)F)C=C5
Renhedsgrad noter	Research
Molekylær formel	C₃₂H₂₈F₃N₅O₄
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 473719-41-4

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