CAS RN 405098-33-1

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MedChemExpress W-54011 is a potent and orally active non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils with a Ki value of 2.2 nM. W-54011 also inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and generation of ROS in human neutrophils with IC50s of 3.1 nM, 2.7 nM, and 1.6 nM, respectively.

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Tekniske data

Kemisk navn eller materiale	W-54011
Formel vægt	493.08
Opløselighedsinformation	DMSO : ≥ 28 mg/mL (56.79 mM)
Procent renhed	98.0%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol)	493.08
CAS	405098-33-1
Holdbarhed	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL	O=C(C1CCCC2=C1C=C(OC)C=C2)N(CC3=CC=C(N(C)C)C=C3)C4=CC=C(C(C)C)C=C4.[H]Cl
Renhedsgrad noter	Research
Molekylær formel	C₃₀H₃₇ClN₂O₂

CAS RN 405098-33-1

W 54011, TRC

W-54011, MedChemExpress

CAS RN 405098-33-1

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