CAS RN 304896-28-4

IUPAC Navn: 2-cyano-3-[5-(2,5-dichlorophenyl)furan-2-yl]-N-(quinolin-5-yl)prop-2-enamide

Synonymer: 2-cyano-3-[5-(2,5-dichlorophenyl)furan-2-yl]-N-(quinolin-5-yl)prop-2-enamide

Molekylvægt (g/mol): 434.28

Molekylformel: C23H13Cl2N3O2

InChi Key: SVENPFFEMUOOGK-UHFFFAOYSA-N

SMILES: ClC1=CC(C2=CC=C(O2)C=C(C#N)C(=O)NC2=C3C=CC=NC3=CC=C2)=C(Cl)C=C1

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MedChemExpress AGK2 is a selective SIRT2 inhibitor with an IC50 of 3.5 μM. AGK2 inhibits SIRT1 and SIRT3 with IC50s of 30 and 91 μM, respectively.

Kemisk navn eller materiale	AGK2
Formel vægt	434.27
Opløselighedsinformation	DMSO : 12.5 mg/mL (28.78 mM; Need ultrasonic)
Procent renhed	97.0%
Fysisk form	Solid
Farve	Green Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	434.27
CAS	304896-28-4
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(NC1=C2C=CC=NC2=CC=C1)/C(C#N)=C/C3=CC=C(C4=CC(Cl)=CC=C4Cl)O3
Renhedsgrad noter	Research
Molekylær formel	C₂₃H₁₃Cl₂N₃O₂
Til brug med (applikation)	Cancer-programmed cell death