CAS RN 2361241-23-6

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BI-749327, MedChemExpress

MedChemExpress BI-749327 is a potent, high selectivity and orally bioavailable TRPC6 antagonist, with IC50s of 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6, respectively. BI-749327 is 85-fold more selective for mouse TRPC6 than TRPC3 and 42-fold versus TRPC7.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	BI-749327
Formel vægt	442.43
Opløselighedsinformation	DMSO : 31.25 mg/mL (70.63 mM; Need ultrasonic)
Procent renhed	98.49%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	442.43
CAS	2361241-23-6
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	NC1=NN=C(C2CCN(C(C3=CC=C(OC4=CC=C(C(F)(F)F)C=C4)C=C3)=O)CC2)C=C1
Renhedsgrad noter	Research
Molekylær formel	C₂₃H₂₁F₃N₄O₂
Til brug med (applikation)	COVID-19-immunoregulation

CAS RN 2361241-23-6

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