CAS RN 2170608-82-7

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PZ-2891, MedChemExpress

MedChemExpress PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator. PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits human pantothenate kinases PANK1β, PANK2, and PANK3 with IC50s of 40.2 nM, 0.7 nM and 1.3 nM, respectively.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	PZ-2891
Formel vægt	349.43
Opløselighedsinformation	DMSO : 75 mg/mL (214.64 mM; Need ultrasonic)
Procent renhed	98.4%
Fysisk form	Solid
Farve	Off-White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	349.43
CAS	2170608-82-7
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	N#CC1=NN=C(N2CCN(C(CC3=CC=C(C(C)C)C=C3)=O)CC2)C=C1
Renhedsgrad noter	Research
Molekylær formel	C₂₀H₂₃N₅O
Til brug med (applikation)	Neuroscience-Neuromodulation

CAS RN 2170608-82-7

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