CAS RN 2064292-12-0

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A1874, MedChemExpress

MedChemExpress A1874 is a nutlin-based (MDM2 ligand) and BRD4-degrading PROTAC with a DC50 of 32 nM (induce BRD4 degradation in cells). Effective in inhibiting many cancer cell lines proliferation.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	A1874
Formel vægt	1173.59
Opløselighedsinformation	DMSO : 150 mg/mL (127.81 mM; Need ultrasonic)
Procent renhed	99.28%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molekylvægt (g/mol)	1173.59
CAS	2064292-12-0
Holdbarhed	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
SMIL	ClC(C=C1)=CC=C1C2=N[C@H](C3=NN=C(C)N3C4=C2C(C)=C(C)S4)CC(NCCOCCOCCOCCNC(C5=CC(OC)=C(NC([C@H]6[C@H](C7=C(F)C(Cl)=CC=C7)[C@](C8=CC=C(Cl)C=C8F)(C#N)[C@H](CC(C)(C)C)N6)=O)C=C5)=O)=O
Renhedsgrad noter	Research
Molekylær formel	C₅₈H₆₂Cl₃F₂N₉O₇S
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 2064292-12-0

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