CAS RN 1991986-30-1

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ML364, MedChemExpress

MedChemExpress ML364 is a selective ubiquitin specific peptidase 2 (USP2) inhibitor (IC50=1.1 μM) with anti-proliferative activity, which direct binds to USP2 (Kd=5.2 μM), induces an increase in cellular cyclin D1 degradation and causes cell cycle arrest. ML364 increases the levels of mitochondrial ROS and decreases in the intracellular content of ATP.

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Tekniske data

Kemisk navn eller materiale	ML364
Formel vægt	517.54
Opløselighedsinformation	DMSO : ≥ 33 mg/mL (63.76 mM)
Procent renhed	99.94%
Fysisk form	Solid
Farve	off White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	517.54
CAS	1991986-30-1
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(NC1=NC(C2=CC=CC=C2)=CS1)C3=CC=C(C(F)(F)F)C=C3NS(=O)(C4=CC=C(C)C=C4)=O
Renhedsgrad noter	Research
Molekylær formel	C₂₄H₁₈F₃N₃O₃S₂
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 1991986-30-1

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