CAS RN 197723-00-5

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NKP-1339, MedChemExpress

MedChemExpress NKP-1339 (IT-139; KP-1339) is the first-in-class ruthenium-based anticancer agent in development against solid cancer with limited side effects. NKP-1339 induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway. NKP-1339 has a high tumor targeting potential, strongly binds to serum proteins such as albumin and transferrin and activates in the reductive tumor milieu.

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Tekniske data

Kemisk navn eller materiale	NKP-1339
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	502.14
Opløselighedsinformation	DMSO : ≥ 59 mg/mL (117.50 mM)
Procent renhed	98.14%
Fysisk form	Solid
Farve	Dark Brown
Grad	Research
Anbefalet opbevaring	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol)	502.14
CAS	197723-00-5
Synonym	IT-139 KP-1339
Holdbarhed	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL	[Cl-][Ru+3]([N]1=CC2=CC=CC=C2N1)([Cl-])([Cl-])([N]3=CC4=CC=CC=C4N3)[Cl-].[Na+]
Renhedsgrad noter	Research
Molekylær formel	C₁₄H₁₂Cl₄N₄NaRu
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 197723-00-5

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