CAS RN 1808160-52-2

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CF53, MedChemExpress

MedChemExpress CF53 is a highly potent, selective and orally active inhibitor of BET protein, with a Ki of Kd of 2.2 nM and an IC50 of 2 nM for BRD4 BD1. CF53 binds to both the BD1 and BD2 domains of BRD2, BRD3, BRD4, and BRDT BET proteins with high affinities, very selective over non-BET bromodomain-containing proteins. CF53 shows potent anti-tumor activity both in vitro and in vivo.

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Tekniske data

Kemisk navn eller materiale	CF53
Formel vægt	443.5
Opløselighedsinformation	DMSO : 110 mg/mL (248.03 mM; Need ultrasonic)
Procent renhed	98.09%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	-20°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molekylvægt (g/mol)	443.5
CAS	1808160-52-2
Holdbarhed	-20°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
SMIL	COC1=C(C2=C(C)ON=C2C)C=C(NC3=C4C(NC5=CC(C6CC6)=NN5C)=NC(C)=N3)C4=C1
Renhedsgrad noter	Research
Molekylær formel	C₂₄H₂₅N₇O₂
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 1808160-52-2

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