CAS RN 1799711-21-9

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Tocris Bioscience™ dBET1

(+)-JQ1 based Degrader (PROTAC™) targeting BET bromodomains, active in vivo

Pris og tilgængelighed

MedChemExpress dBET1 is a PROTAC connected by ligands for Cereblon and BRD4 with an EC50 of 430 nM. dBET1 is a PROTAC that composes of (+)-JQ1 (HY-13030) linked to NSC 527179 (HY-14658) with a linker.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	dBET1
Formel vægt	785.27
Opløselighedsinformation	DMSO : 43.33 mg/mL (55.18 mM; Need ultrasonic)
Procent renhed	98.09%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	785.27
CAS	1799711-21-9
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(NCCCCNC(COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)=O)C[C@H]4C5=NN=C(C)N5C6=C(C(C)=C(C)S6)C(C7=CC=C(Cl)C=C7)=N4
Renhedsgrad noter	Research
Molekylær formel	C₃₈H₃₇ClN₈O₇S
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 1799711-21-9

Tocris Bioscience™ dBET1

dBET1, TRC

dBET1, MedChemExpress

CAS RN 1799711-21-9

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Snævre resultater

Tocris Bioscience™ dBET1 Greener Choice ProductThis product offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”Learn More About the Greener Choice Program

Tocris Bioscience™ dBET1