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H3CCH3(R)HNO(S)NHONNBOHHO

CAS RN 179324-69-7

IUPAC Navn: [(1R)-3-methyl-1-[(2S)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamido]butyl]boronic acid
Synonymer: bortezomib velcade
Molekylvægt (g/mol): 384.24
Molekylformel: C19H25BN4O4
InChi Key: GXJABQQUPOEUTA-RDJZCZTQSA-N
SMILES: CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CN=CC=N1)B(O)O
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1 – 4 af 4 Resultater
1

Bortezomib, TRC

CAS: 179324-69-7 Molekylær formel: C19 H25 B N4 O4 Molekylvægt (g/mol): 384.24 Synonym: Boronic acid, B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-,Boronic acid, [(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]- (9CI),Boronic acid, [3-methyl-1-[[1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]-, [S-(R*,S*)]-,Bortezomib,DPBA,LDP 341,MG 341,MLN 341,NSC 681239,PS 314,PS 341,PS 341 (pharmaceutical),Radiciol,Velcade IUPAC navn: [(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid SMIL: CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c2cnccn2)B(O)O

Molekylvægt (g/mol) 384.24
CAS 179324-69-7
Synonym Boronic acid, B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-,Boronic acid, [(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]- (9CI),Boronic acid, [3-methyl-1-[[1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]-, [S-(R*,S*)]-,Bortezomib,DPBA,LDP 341,MG 341,MLN 341,NSC 681239,PS 314,PS 341,PS 341 (pharmaceutical),Radiciol,Velcade
SMIL CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c2cnccn2)B(O)O
IUPAC navn [(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid
Molekylær formel C19 H25 B N4 O4
2

Tocris Bioscience™ Bortezomib
GREENER_CHOICE

High affinity proteasome inhibitor

Kemisk navn eller materiale B-[(1 R)-3-Methyl-1-[[(2 S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid
Anbefalet opbevaring Store at -20°C
CAS 179324-69-7
Mål Proteasome Inhibitors
Renhed 0.98
Molekylær formel C19H25BN4O4
3

Bortezomib, MedChemExpress

MedChemExpress Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Anti-cancer activity.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Bortezomib
Sundhedsfare 1 H300∣H315∣H319∣H361∣H372∣H411
Formel vægt 384.24
Opløselighedsinformation Ethanol : 66.67 mg/mL (173.51 mM; ultrasonic and warming and heat to 60°C) ∣DMSO : 50 mg/mL (130.13 mM; Need ultrasonic)
Procent renhed 98.0%
Fysisk form Solid
Farve White
Grad Research
Anbefalet opbevaring 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Molekylvægt (g/mol) 384.24
CAS 179324-69-7
Synonym PS-341 LDP-341 NSC 681239
Holdbarhed 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
SMIL OB(O)[C@H](CC(C)C)NC([C@@H](NC(C1=NC=CN=C1)=O)CC2=CC=CC=C2)=O
Renhedsgrad noter Research
Molekylær formel C19H25BN4O4
Til brug med (applikation) Cancer-Kinase/protease
4

Bortezomib, 98%

CAS: 179324-69-7 Molekylær formel: C19H25BN4O4 Molekylvægt (g/mol): 384.243 MDL nummer: MFCD09056737 InChI nøgle: GXJABQQUPOEUTA-RDJZCZTQSA-N Synonym: bortezomib,velcade,bortezomib ps-341,dpba,pyz-phe-boroleu,unii-69g8bd63pp,velcade tn,bortezomib velcade,1r-3-methyl-1-2s-1-oxo-3-phenyl-2-pyrazinylcarbonyl amino propyl amino butyl boronic acid,1r-3-methyl-1-2s-3-phenyl-2-pyrazine-2-carbonylamino propanoyl amino butyl boronic acid PubChem CID: 387447 ChEBI: CHEBI:52717 IUPAC navn: [(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid SMIL: B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O

MDL nummer MFCD09056737
PubChem CID 387447
Molekylvægt (g/mol) 384.243
CAS 179324-69-7
ChEBI CHEBI:52717
Synonym bortezomib,velcade,bortezomib ps-341,dpba,pyz-phe-boroleu,unii-69g8bd63pp,velcade tn,bortezomib velcade,1r-3-methyl-1-2s-1-oxo-3-phenyl-2-pyrazinylcarbonyl amino propyl amino butyl boronic acid,1r-3-methyl-1-2s-3-phenyl-2-pyrazine-2-carbonylamino propanoyl amino butyl boronic acid
SMIL B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
IUPAC navn [(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid
InChI nøgle GXJABQQUPOEUTA-RDJZCZTQSA-N
Molekylær formel C19H25BN4O4