CAS RN 1642303-38-5

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MedChemExpress ITI-214 is a potent, CNS-active, orally bioavailable PDE1 inhibitor (Ki of 58 pM) with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters and ion channels. ITI-214 inhibits recombinant full-length human PDE1A, PDE1B and PDE1C with Kis of 33 pM, 380 pM and 35 pM, respectively. ITI-214 shows efficacy in various animal models of motor and cognitive functions.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	ITI-214
Formel vægt	605.56
Opløselighedsinformation	DMSO : ≥ 30 mg/mL (49.54 mM)
Procent renhed	99.54%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol)	605.56
CAS	1642303-38-5
Holdbarhed	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL	O=C(C1=C(NC2=CC=CC=C2)N(CC3=CC=C(C4=NC(F)=CC=C4)C=C3)N=C1N56)N(C)C5=N[C@@]7([H])[C@]6([H])CCC7.O=P(O)(O)O
Renhedsgrad noter	Research
Molekylær formel	C₂₉H₂₉FN₇O₅P
Til brug med (applikation)	Neuroscience-Neuromodulation

CAS RN 1642303-38-5

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