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ITI-214, MedChemExpress

Artikelnummer. 16491427
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Mængde:
5 mg
10 mg
50 mg
Pakningsstørrelse:
50mg
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16491427 50 mg 50mg
16477937 5 mg -
16435218 10 mg -
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Artikelnummer. 16491427 Leverandør Medchem Express Leverandørnr. HY12501A

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Beskrivelse

MedChemExpress ITI-214 is a potent, CNS-active, orally bioavailable PDE1 inhibitor (Ki of 58 pM) with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters and ion channels. ITI-214 inhibits recombinant full-length human PDE1A, PDE1B and PDE1C with Kis of 33 pM, 380 pM and 35 pM, respectively. ITI-214 shows efficacy in various animal models of motor and cognitive functions.

ITI-214 is a potent, CNS-active, orally bioavailable PDE1 inhibitor (Ki of 58 pM) with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters and ion channels. ITI-214 inhibits recombinant full-length human PDE1A, PDE1B and PDE1C with Kis of 33 pM, 380 pM and 35 pM, respectively. ITI-214 shows efficacy in various animal models of motor and cognitive functions.

Tekniske data

Kemisk navn eller materiale ITI-214
CAS 1642303-38-5
Farve White
Renhedsgrad noter Research
Molekylær formel C29H29FN7O5P
Mængde 50 mg
Opløselighedsinformation DMSO : ≥ 30 mg/mL (49.54 mM)
SMIL O=C(C1=C(NC2=CC=CC=C2)N(CC3=CC=C(C4=NC(F)=CC=C4)C=C3)N=C1N56)N(C)C5=N[C@@]7([H])[C@]6([H])CCC7.O=P(O)(O)O
Molekylvægt (g/mol) 605.56
Formel vægt 605.56
Procent renhed 99.54%
Grad Research
Fysisk form Solid
Til brug med (applikation) Neuroscience-Neuromodulation
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Research purposes only

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