CAS RN 1627709-94-7

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Tocris Bioscience™ LJI308

Potent pan-ribosomal S6 protein kinase (RSK) inhibitor (IC50 values are 4 to 13 nM)

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	2,6-Difluoro-4-[4-[4-(4-morpholinyl)phenyl]-3-pyridinyl]phenol
Anbefalet opbevaring	Store at -20°C
CAS	1627709-94-7
Formel vægt	368.38
Renhed	98%
Molekylær formel	C₂₁H₁₈F₂N₂O₂

MedChemExpress LJI308 is a potent pan-ribosomal S6 kinase (RSK) inhibitor, with IC50s of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. LJI308 inhibits the phosphorylation of RSK (T359/S363) and YB-1 (S102) after irradiation, treatment with EGF, and in cells expressing a KRAS mutation.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	LJI308
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	368.38
Opløselighedsinformation	DMSO : 25 mg/mL (67.86 mM; Need ultrasonic)
Procent renhed	99.21%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	368.38
CAS	1627709-94-7
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	OC1=C(F)C=C(C2=C(C3=CC=C(N4CCOCC4)C=C3)C=CN=C2)C=C1F
Renhedsgrad noter	Research
Molekylær formel	C₂₁H₁₈F₂N₂O₂
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 1627709-94-7

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Tocris Bioscience™ LJI308 Greener Choice ProductThis product offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”Learn More About the Greener Choice Program

Tocris Bioscience™ LJI308