accessibility menu, dialog, popup

UserName
CH3H3CNHNOHNCH3H3CCH3ONNNH2NBrOHOH

CAS RN 1561178-17-3

IUPAC Navn: 3-(3-{[(5-{4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-3,4-dihydroxyoxolan-2-yl)methyl](propan-2-yl)amino}propyl)-1-(4-tert-butylphenyl)urea
Synonymer: 3-(3-{[(5-{4-amino-5-bromopyrrolo[2,3-d]pyrimidin-7-yl}-3,4-dihydroxyoxolan-2-yl)methyl](isopropyl)amino}propyl)-1-(4-tert-butylphenyl)urea
Molekylvægt (g/mol): 618.58
Molekylformel: C28H40BrN7O4
InChi Key: IQCKJUKAQJINMK-UHFFFAOYNA-N
SMILES: CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)CC1OC(C(O)C1O)N1C=C(Br)C2=C(N)N=CN=C12
Molekylvægt (g/mol) 
  • (6)
Mængde 
  • (2)
  • (1)
  • (2)
  • (1)
Grad 
  • (3)
Procent renhed 
  • (3)
Fysisk form 
  • (3)

Filtrerede søgeresultater

Produkter fra nogle af vores leverandører vises ikke i filtrerede søgeresultater. ryd alle filtre for at se disse produkter.

Snævre resultater

Snævre resultater

Kategori

Brands

  • (3)
  • (1)
  • (3)

specielle programmer

  • (3)
  • (1)

Molekylvægt (g/mol)

  • (6)

Mængde

  • (2)
  • (1)
  • (2)
  • (1)

Grad

  • (3)

Procent renhed

  • (3)

Fysisk form

  • (3)
1 – 3 af 3 Resultater
1

SGC-0946, TRC

CAS: 1561178-17-3 Molekylær formel: C28H40BrN7O4 Molekylvægt (g/mol): 618.57 Synonym: SGC-0946,5-Bromo-7-[5-deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine IUPAC navn: 1-[3-[[(2R,3S,4R,5R)-5-(4-amino-5-bromopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxyoxolan-2-yl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urea SMIL: CC(C)N(CCCNC(=O)Nc1ccc(cc1)C(C)(C)C)C[C@H]2O[C@H]([C@H](O)[C@@H]2O)n3cc(Br)c4c(N)ncnc34

Molekylvægt (g/mol) 618.57
CAS 1561178-17-3
Synonym SGC-0946,5-Bromo-7-[5-deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
SMIL CC(C)N(CCCNC(=O)Nc1ccc(cc1)C(C)(C)C)C[C@H]2O[C@H]([C@H](O)[C@@H]2O)n3cc(Br)c4c(N)ncnc34
IUPAC navn 1-[3-[[(2R,3S,4R,5R)-5-(4-amino-5-bromopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxyoxolan-2-yl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urea
Molekylær formel C28H40BrN7O4
2

Tocris Bioscience™ SGC 0946
GREENER_CHOICE

Highly potent and selective DOT1L inhibitor; cell permeable

3

SGC0946, MedChemExpress

MedChemExpress SGC0946 is a selective DOT1LH3K79 methyltransferase) inhibitor, with an IC50 of 0.3 nM. SGC0946 results in G1 arrest, inhibits potential of cell self-renewal and metastatic, also induces cell differentiation. SGC0946 can be used in studies of leukemia and solid tumors and also serve as a probe to further investigate the cellular mechanism of DOT1L in both normal and diseased cells.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale SGC0946
Sundhedsfare 1 H301
Formel vægt 618.57
Opløselighedsinformation DMSO : 50 mg/mL (80.83 mM; Need ultrasonic)
Procent renhed 98.0%
Fysisk form Solid
Farve Light Nude
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 618.57
CAS 1561178-17-3
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL NC1=NC=NC2=C1C(Br)=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CN(CCCNC(NC4=CC=C(C(C)(C)C)C=C4)=O)C(C)C)O3
Renhedsgrad noter Research
Molekylær formel C28H40BrN7O4
Til brug med (applikation) Cancer-programmed cell death