CAS RN 147254-64-6

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Ranirestat, MedChemExpress

MedChemExpress Ranirestat (AS-3201) potent and orally active aldose reductase (AR) inhibitor with IC50s of 11 nM and 15 nM for rat lens AR and recombinant human AR, respectively, and a Ki of 0.38 nM for recombinant human AR. Ranirestat has the potential for diabetic sensorimotor polyneuropathy treatment. Ranirestat also has a neuroprotective effect on diabetic retinas.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Ranirestat
Sundhedsfare 1	H315∣H319∣H335
Formel vægt	420.19
Opløselighedsinformation	DMSO : ≥ 50 mg/mL (118.99 mM)
Procent renhed	98.32%
Fysisk form	Solid
Farve	Off-White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	420.19
CAS	147254-64-6
Synonym	AS-3201
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(N1CC2=CC=C(Br)C=C2F)C3=CC=CN3[C@]4(C(NC(C4)=O)=O)C1=O
Renhedsgrad noter	Research
Molekylær formel	C₁₇H₁₁BrFN₃O₄
Til brug med (applikation)	Metabolism-sugar/lipid metabolism

CAS RN 147254-64-6

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