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Ranirestat, MedChemExpress

Artikelnummer. 16492547
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100mg
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Artikelnummer. 16492547 Leverandør Medchem Express Leverandørnr. HY15314

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Beskrivelse

MedChemExpress Ranirestat (AS-3201) potent and orally active aldose reductase (AR) inhibitor with IC50s of 11 nM and 15 nM for rat lens AR and recombinant human AR, respectively, and a Ki of 0.38 nM for recombinant human AR. Ranirestat has the potential for diabetic sensorimotor polyneuropathy treatment. Ranirestat also has a neuroprotective effect on diabetic retinas.

Ranirestat (AS-3201) potent and orally active aldose reductase (AR) inhibitor with IC50s of 11 nM and 15 nM for rat lens AR and recombinant human AR, respectively, and a Ki of 0.38 nM for recombinant human AR. Ranirestat has the potential for diabetic sensorimotor polyneuropathy treatment. Ranirestat also has a neuroprotective effect on diabetic retinas.

Tekniske data

Kemisk navn eller materiale Ranirestat
CAS 147254-64-6
Farve Off-White
Renhedsgrad noter Research
Molekylær formel C17H11BrFN3O4
Mængde 50 mg
Synonym AS-3201
Opløselighedsinformation DMSO : ≥ 50 mg/mL (118.99 mM)
SMIL O=C(N1CC2=CC=C(Br)C=C2F)C3=CC=CN3[C@]4(C(NC(C4)=O)=O)C1=O
Molekylvægt (g/mol) 420.19
Formel vægt 420.19
Procent renhed 98.32%
Grad Research
Fysisk form Solid
Til brug med (applikation) Metabolism-sugar/lipid metabolism
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Research purposes only

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