CAS RN 1454682-72-4

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MedChemExpress LY3009120 (DP-4978) is a pan RAF inhibitor which inhibits BRAFV600E, BRAFWT and CRAFWT with IC50s of 5.8, 9.1 and 15 nM, respectively.

Kemisk navn eller materiale	LY3009120
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	424.51
Opløselighedsinformation	DMSO : ≥ 38 mg/mL (89.51 mM)
Procent renhed	98.66%
Fysisk form	Solid
Farve	Earth Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	424.51
CAS	1454682-72-4
Synonym	DP-4978
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(NC1=CC(C2=CC3=CN=C(NC)N=C3N=C2C)=C(C)C=C1F)NCCC(C)(C)C
Renhedsgrad noter	Research
Molekylær formel	C₂₃H₂₉FN₆O
Til brug med (applikation)	Cancer-Kinase/protease