CAS RN 1450833-55-2

IUPAC Navn: —

Synonymer: —

Molekylvægt (g/mol): —

Molekylformel: —

InChi Key: —

SMILES: —

MedChemExpress TAK-243 (MLN7243) is a first-in-class, selective ubiquitin activating enzyme, UAE (UBA1) inhibitor (IC50=1 nM), which blocks ubiquitin conjugation, disrupting monoubiquitin signaling as well as global protein ubiquitination. TAK-243 (MLN7243) induces endoplasmic reticulum (ER) stress, abrogates NF-κB pathway activation and promotes apoptosis.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	TAK-243
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	519.52
Opløselighedsinformation	DMSO : 50 mg/mL (96.24 mM; Need ultrasonic) ∣H2O : 1 mg/mL (1.92 mM; Need ultrasonic)
Procent renhed	98.0%
Fysisk form	Solid
Farve	Off-White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	519.52
CAS	1450833-55-2
Synonym	MLN7243
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=S(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](NC2=CC=NC3=CC(C4=CC=CC(SC(F)(F)F)=C4)=NN23)C1)(N)=O
Renhedsgrad noter	Research
Molekylær formel	C₁₉H₂₀F₃N₅O₅S₂
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 1450833-55-2

Filtrerede søgeresultater

Snævre resultater