CAS RN 1446700-26-0

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Rociletinib hydrobromide, MedChemExpress

MedChemExpress Rociletinib hydrobromide (CO-1686 hydrobromide) is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the Ki values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Rociletinib hydrobromide
Formel vægt	636.46
Opløselighedsinformation	DMSO : ≥ 59 mg/mL (92.70 mM) ∣H2O : < 0.1 mg/mL (insoluble)
Procent renhed	98.04%
Fysisk form	Solid
Farve	Yellow
Grad	Research
Anbefalet opbevaring	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol)	636.46
CAS	1446700-26-0
Synonym	CO-1686 hydrobromide AVL-301 hydrobromide CNX-419 hydrobromide
Holdbarhed	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL	C=CC(NC1=CC=CC(NC2=NC(NC3=CC=C(N4CCN(C(C)=O)CC4)C=C3OC)=NC=C2C(F)(F)F)=C1)=O.[H]Br
Renhedsgrad noter	Research
Molekylær formel	C₂₇H₂₉BrF₃N₇O₃
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 1446700-26-0

CAS RN 1446700-26-0

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