CAS RN 1369665-02-0

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Cobimetinib hemifumarate, MedChemExpress

MedChemExpress Cobimetinib hemifumarate is a novel selective MEK1 inhibitor, and the IC50 value against MEK1 is 4.2 nM.

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Tekniske data

Kemisk navn eller materiale	Cobimetinib hemifumarate
Formel vægt	589.25
Opløselighedsinformation	DMSO : 50 mg/mL (84.85 mM; Need ultrasonic) ∣H2O : 1 mg/mL (1.70 mM; ultrasonic and warming and heat to 60°C)
Procent renhed	96.76%
Fysisk form	Solid
Farve	Off-White
Grad	Research
Anbefalet opbevaring	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol)	589.25
CAS	1369665-02-0
Synonym	GDC-0973 hemifumarateXL-518 hemifumarate
Holdbarhed	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL	OC1(CN(C(C2=C(NC3=C(F)C=C(I)C=C3)C(F)=C(F)C=C2)=O)C1)[C@H]4NCCCC4.O=C(/C=C/C(O)=O)O.[0.5]
Renhedsgrad noter	Research
Molekylær formel	C₂₁H₂₁F₃IN₃O₂.₁/₂C₄H₄O₄
Til brug med (applikation)	Cancer-Kinase/protease