CAS RN 1363281-27-9

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Selective mGlu5 positive allosteric modulator; brain penetrant and orally bioavailable

Kemisk navn eller materiale	[6,7-Dihydro-2-(phenoxymethyl)oxazolo[5,4-c]pyridin-5(4H)-yl](fluorophenyl)methanone
Anbefalet opbevaring	Store at 4°C
CAS	1363281-27-9
Formel vægt	352.36
Mål	Group I mGluR Modulators
Synonym	JNJ 46778212
Renhed	>98%
Molekylær formel	C₂₀H₁₇FN₂O₃

MedChemExpress JNJ-46778212 (VU 0409551) is an mGlu5 positive allosteric modulator with an EC50 of 260 nM.

Kemisk navn eller materiale	JNJ-46778212
Formel vægt	352.36
Opløselighedsinformation	DMSO : ≥ 125 mg/mL (354.75 mM)
Procent renhed	99.46%
Fysisk form	Solid
Farve	Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	352.36
CAS	1363281-27-9
Synonym	VU 0409551
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(N1CCC2=C(OC(COC3=CC=CC=C3)=N2)C1)C4=CC=C(F)C=C4
Renhedsgrad noter	Research
Molekylær formel	C₂₀H₁₇FN₂O₃
Til brug med (applikation)	Neuroscience-Neurodegeneration

Selective mGlu5 positive allosteric modulator; brain penetrant and orally bioavailable

Selective mGlu5 positive allosteric modulator; brain penetrant and orally bioavailable