CAS RN 1346547-00-9

IUPAC Navn: N-(5-fluoro-1H-indazol-3-yl)-6-(2-methylpropane-2-sulfonyl)quinolin-4-amine

Synonymer: N-(5-fluoro-1H-indazol-3-yl)-6-(2-methylpropane-2-sulfonyl)quinolin-4-amine

Molekylvægt (g/mol): 398.46

Molekylformel: C20H19FN4O2S

InChi Key: XLOGLWKOHPIJLV-UHFFFAOYSA-N

SMILES: CC(C)(C)S(=O)(=O)C1=CC=C2N=CC=C(NC3=NNC4=CC=C(F)C=C34)C2=C1

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Thermo Scientific™ GSK583, 95%

Pris og tilgængelighed

Tocris Bioscience™ GSK 583

Potent RIP2 kinase inhibitor; orally bioavailable and cell permeable

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	6-[(1,1-Dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)-4-quinolinamine
Anbefalet opbevaring	Store at -20°C
CAS	1346547-00-9
Renhed	98%
Molekylær formel	C₂₀H₁₉FN₄O₂S

GSK583, MedChemExpress

MedChemExpress GSK583 is a highly potent, orally active and selective inhibitor of RIP2 Kinase, with IC50 of 5 nM. GSK583 inhibits both TNF-α and IL-6 production with an IC50 value of 200 nM.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	GSK583
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	398.45
Opløselighedsinformation	DMSO : ≥ 100 mg/mL (250.97 mM)
Procent renhed	98.74%
Fysisk form	Solid
Farve	Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	398.45
CAS	1346547-00-9
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	FC1=CC2=C(NN=C2NC3=CC=NC4=CC=C(S(=O)(C(C)(C)C)=O)C=C34)C=C1
Renhedsgrad noter	Research
Molekylær formel	C₂₀H₁₉FN₄O₂S
Til brug med (applikation)	COVID-19-immunoregulation

CAS RN 1346547-00-9

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Tocris Bioscience™ GSK 583 Greener Choice ProductThis product offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”Learn More About the Greener Choice Program

Tocris Bioscience™ GSK 583