CAS RN 1336960-13-4

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Potent and selective TRPV4 antagonist; orally active

Analyseprocentområde	>98%
Kemisk navn eller materiale	3-([1,4'-Bipiperidin]-1'-ylmethyl)-7-bromo-N-(1-phenylcyclopropyl)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxamide
Anbefalet opbevaring	Store at 4°C
CAS	1336960-13-4
Formel vægt	Observed MW: 691.62
Molekylær formel	C₃₇H₃₈BrF₃N₄O

MedChemExpress GSK2193874 is an orally active, potent, and selective TRPV4 antagonist with IC50s of 2 nM and 40 nM for rTRPV4 and hTRPV4.

Kemisk navn eller materiale	GSK2193874
Sundhedsfare 1	H301∣H315∣H319∣H335
Formel vægt	691.62
Opløselighedsinformation	DMSO : 100 mg/mL (144.59 mM; Need ultrasonic)
Procent renhed	98.33%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	691.62
CAS	1336960-13-4
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(C1=C(CN2CCC(N3CCCCC3)CC2)C(C4=CC=CC(C(F)(F)F)=C4)=NC5=CC(Br)=CC=C15)NC6(C7=CC=CC=C7)CC6
Renhedsgrad noter	Research
Molekylær formel	C₃₇H₃₈BrF₃N₄O
Til brug med (applikation)	COVID-19-immunoregulation

Potent and selective TRPV4 antagonist; orally active