CAS RN 1303607-60-4

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SAR405838, MedChemExpress

MedChemExpress SAR405838 (MI-77301), an analog of MI-773, is a highly potent and selective MDM2-p53 interaction inhibitor. SAR405838 binds to MDM2 with a Ki of 0.88 nM. SAR405838 induces apoptosis and has potent antitumor activity.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	SAR405838
Formel vægt	562.5
Opløselighedsinformation	DMSO : 100 mg/mL (177.78 mM; Need ultrasonic)
Procent renhed	95.0%
Fysisk form	Solid
Farve	Off-White
Grad	Research
Anbefalet opbevaring	-20°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol)	562.5
CAS	1303607-60-4
Synonym	MI-77301
Holdbarhed	-20°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL	O=C([C@H](N[C@H]1CC(C)(C)C)[C@H](C2=CC=CC(Cl)=C2F)[C@@]31C(NC4=C3C=CC(Cl)=C4)=O)N[C@@H]5CC[C@@H](O)CC5
Renhedsgrad noter	Research
Molekylær formel	C₂₉H₃₄Cl₂FN₃O₃
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 1303607-60-4

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