CAS RN 1286739-19-2

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Potent group I PAK inhibitor

Kemisk navn eller materiale	FRAX 597
Anbefalet opbevaring	Store at -20°C
CAS	1286739-19-2
Formel vægt	558.1
Mål	PAK Inhibitors
Produkttype	Bioactive Small Molecule
Synonym	6-[2-Chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7-(8H)-one
Opløselighed	Soluble to 20mM in DMSO
Renhed	>98%
Fysisk form	Solid
Farve	Yellow
Molekylær formel	C₂₉H₂₈ClN₇OS

MedChemExpress FRAX597 is a potent group I p21-activated Kinases (PAKs) inhibitor with IC50 of 8, 13 and 19 nM for PAK1, 2 and 3.

Kemisk navn eller materiale	FRAX597
Formel vægt	558.1
Opløselighedsinformation	DMSO : 14.29 mg/mL (25.60 mM; Need ultrasonic)
Procent renhed	98.55%
Fysisk form	Solid
Farve	Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	558.1
CAS	1286739-19-2
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C1C(C2=CC=C(C3=CN=CS3)C=C2Cl)=CC4=CN=C(NC5=CC=C(N6CCN(C)CC6)C=C5)N=C4N1CC
Renhedsgrad noter	Research
Molekylær formel	C₂₉H₂₈ClN₇OS
Til brug med (applikation)	Cancer-Kinase/protease

Potent group I PAK inhibitor

Potent group I PAK inhibitor