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CAS RN 1265916-41-3

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1

BIX 02189, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

2

BIX 02189, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

Kemisk navn eller materiale (3Z)-3-[((3-[(Dimethylamino)methyl]phenyl)amino)phenylmethylene]-2,3-dihydro-N,N-dimethyl-2-oxo-1H-indole-6-carboxamide
Anbefalet opbevaring -20°C
Molekylvægt (g/mol) 440.54
InChI formel InChI=1S/C27H28N4O2/c1-30(2)17-18-9-8-12-21(15-18)28-25(19-10-6-5-7-11-19)24-22-14-13-20(27(33)31(3)4)16-23(22)29-26(24)32/h5-16,29,32H,17H2,1-4H3
CAS 1265916-41-3
Synonym BIX 02189,(3Z)-3-[[[3-[(Dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-N,N-dimethyl-2-oxo-1H-indole-6-carboxamide
SMIL CN(C)Cc1cccc(N\C(=C\2/C(=O)Nc3cc(ccc23)C(=O)N(C)C)\c4ccccc4)c1
IUPAC navn 3-[N-[3-[(dimethylamino)methyl]phenyl]-C-phenylcarbonimidoyl]-2-hydroxy-N,N-dimethyl-1H-indole-6-carboxamide
Molekylær formel C27H28N4O2
3

BIX02189, MedChemExpress

MedChemExpress BIX02189 is a potent and selective MEK5 inhibitor with an IC50 of 1.5 nM. BIX02189 also inhibits ERK5 catalytic activity with an IC50 of 59 nM.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale BIX02189
Sundhedsfare 1 H302∣H315∣H319∣H335
Formel vægt 440.54
Opløselighedsinformation DMSO : ≥ 49.4 mg/mL (112.14 mM)
Procent renhed 99.57%
Fysisk form Solid
Farve Yellow
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 440.54
CAS 1265916-41-3
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C(N(C)C)C1=CC(NC2=O)=C(/C2=C(C3=CC=CC=C3)/NC4=CC=CC(CN(C)C)=C4)C=C1.[(Z)]
Renhedsgrad noter Research
Molekylær formel C27H28N4O2
Til brug med (applikation) Cancer-Kinase/protease