CAS RN 1257628-77-5

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Olverembatinib, MedChemExpress

MedChemExpress Olverembatinib (GZD824) is a potent and orally active pan-Bcr-Abl inhibitor. Olverembatinib potently inhibits a broad spectrum of Bcr-Abl mutants. Olverembatinib strongly inhibits native Bcr-Abl and Bcr-AblT315I with IC50s of 0.34 nM and 0.68 nM, respectively. Olverembatinib has antitumor activity.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Olverembatinib
Formel vægt	532.56
Opløselighedsinformation	DMSO : 50 mg/mL (93.89 mM; Need ultrasonic)
Procent renhed	99.46%
Fysisk form	Powder
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	532.56
CAS	1257628-77-5
Synonym	GZD824 HQP1351
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(NC1=CC=C(CN2CCN(C)CC2)C(C(F)(F)F)=C1)C3=CC=C(C)C(C#CC4=CN=C(NN=C5)C5=C4)=C3
Renhedsgrad noter	Research
Molekylær formel	C₂₉H₂₇F₃N₆O
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 1257628-77-5

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