CAS RN 1197196-48-7

IUPAC Navn: 7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine

Synonymer: 7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine

Molekylvægt (g/mol): 485.68

Molekylformel: C26H43N7O2

InChi Key: XIVUGRBSBIXXJE-UHFFFAOYSA-N

SMILES: COC1=CC2=C(NC3CCN(C)CC3)N=C(N=C2C=C1OCCCN(C)C)N1CCCN(C)CC1

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Tocris Bioscience™ UNC 0224

CAS: 1197196-48-7 Molekylær formel: C26H43N7O2

Pris og tilgængelighed
Tekniske data

CAS	1197196-48-7
Molekylær formel	C26H43N7O2

MedChemExpress UNC0224 is a potent and selective histone methyltransferase G9a inhibitor with a Ki of 2.6 nM, an IC50 of 15 nM and a Kd of 23 nM. UNC0224 also potently inhibits b>GLP with assay-dependent IC50 values of 20-58 nM. UNC0224 is inactive against SET7/9, SET8/PreSET7, PRMT3 and JMJD2E.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	UNC0224
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	485.67
Opløselighedsinformation	DMSO : 16.67 mg/mL (34.32 mM; Need ultrasonic)
Procent renhed	98.0%
Fysisk form	Powder
Farve	Off-White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	485.67
CAS	1197196-48-7
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	CN1CCC(NC2=C3C=C(OC)C(OCCCN(C)C)=CC3=NC(N4CCN(C)CCC4)=N2)CC1
Renhedsgrad noter	Research
Molekylær formel	C₂₆H₄₃N₇O₂
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 1197196-48-7

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