CAS RN 1196541-47-5

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MedChemExpress GDC-0575 (ARRY-575, RG7741) is a highly-selective oral small-molecule Chk1 inhibitor with an IC50 of 1.2 nM.

Kemisk navn eller materiale	GDC-0575
Formel vægt	378.27
Opløselighedsinformation	DMSO : 100 mg/mL (264.36 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
Procent renhed	99.5%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	378.27
CAS	1196541-47-5
Synonym	ARRY-575 RG7741
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(C1CC1)NC2=CNC3=NC=C(Br)C(N4C[C@H](N)CCC4)=C32
Renhedsgrad noter	Research
Molekylær formel	C₁₆H₂₀BrN₅O
Til brug med (applikation)	Cancer-Kinase/protease