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H3CONOH3CONHOOHNFOOHOHOOH

CAS RN 1140909-48-3

IUPAC Navn: 2-hydroxybutanedioic acid; N'1-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Synonymer: cabozantinib; malic acid
Molekylvægt (g/mol): 635.6
Molekylformel: C32H30FN3O10
InChi Key: HFCFMRYTXDINDK-UHFFFAOYNA-N
SMILES: OC(CC(O)=O)C(O)=O.COC1=C(OC)C=C2C(OC3=CC=C(NC(=O)C4(CC4)C(=O)NC4=CC=C(F)C=C4)C=C3)=CC=NC2=C1
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1 – 4 af 4 Resultater
1

Cabozantinib (S)-malat, Thermo Scientific™

CAS: 1140909-48-3 Molekylær formel: C32H30FN3O10 Molekylvægt (g/mol): 635.60 MDL nummer: MFCD20923480 InChI nøgle: HFCFMRYTXDINDK-UHFFFAOYNA-N IUPAC navn: 2-hydroxybutandisyre; N'1-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N1-(4-fluorphenyl)cyclopropan-1,1-dicarboxamid SMIL: OC(CC(O)=O)C(O)=O.COC1=C(OC)C=C2C(OC3=CC=C(NC(=O)C4(CC4)C(=O)NC4=CC=C(F)C=C4)C=C3)=CC=NC2=C1

MDL nummer MFCD20923480
Molekylvægt (g/mol) 635.60
CAS 1140909-48-3
SMIL OC(CC(O)=O)C(O)=O.COC1=C(OC)C=C2C(OC3=CC=C(NC(=O)C4(CC4)C(=O)NC4=CC=C(F)C=C4)C=C3)=CC=NC2=C1
IUPAC navn 2-hydroxybutandisyre; N'1-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N1-(4-fluorphenyl)cyclopropan-1,1-dicarboxamid
InChI nøgle HFCFMRYTXDINDK-UHFFFAOYNA-N
Molekylær formel C32H30FN3O10
2

Cabozantinib (S)-Malate, Mikromol™

Discover Mikromol - your trusted source for high-quality pharmaceutical reference standards. Supporting accurate, compliant analysis with ISO 17034-accredited materials designed for confidence in every result.

3

Cabozantinib L-Malate Salt, TRC

CAS: 1140909-48-3 Molekylær formel: C28 H24 F N3 O5 . C4 H6 O5 Molekylvægt (g/mol): 635.59 Synonym: Butanedioic acid, 2-hydroxy-, (2S)-, compd. with N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1),Cabozantinib S-malate,Cabozantinib s-malate,Cometriq,XL 184,Cabozantinib L-malate salt,Cabozantinib (S)-malate IUPAC navn: 1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;(2S)-2-hydroxybutanedioic acid SMIL: COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc5ccc(F)cc5)cc3)c2cc1OC.O[C@@H](CC(=O)O)C(=O)O

Molekylvægt (g/mol) 635.59
CAS 1140909-48-3
Synonym Butanedioic acid, 2-hydroxy-, (2S)-, compd. with N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1),Cabozantinib S-malate,Cabozantinib s-malate,Cometriq,XL 184,Cabozantinib L-malate salt,Cabozantinib (S)-malate
SMIL COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc5ccc(F)cc5)cc3)c2cc1OC.O[C@@H](CC(=O)O)C(=O)O
IUPAC navn 1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;(2S)-2-hydroxybutanedioic acid
Molekylær formel C28 H24 F N3 O5 . C4 H6 O5
4

Cabozantinib S-malate, MedChemExpress

MedChemExpress Cabozantinib S-malate (XL184 S-malate) is a potent multiple receptor tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Cabozantinib S-malate
Formel vægt 635.59
Opløselighedsinformation DMSO : ≥ 23 mg/mL (36.19 mM) ∣H2O : < 0.1 mg/mL (insoluble)
Procent renhed 99.29%
Fysisk form Solid
Farve White
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 635.59
CAS 1140909-48-3
Synonym XL184 S-malateBMS-907351 S-malate
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C([C@H](CC(O)=O)O)O.O=C(NC1=CC=C(C=C1)OC2=CC=NC3=CC(OC)=C(C=C23)OC)C4(CC4)C(NC5=CC=C(C=C5)F)=O
Renhedsgrad noter Research
Molekylær formel C32H30FN3O10
Til brug med (applikation) Cancer-Kinase/protease