CAS RN 1089283-49-7

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MedChemExpress GSK1904529A is a potent, selective, orally active, and ATP-competitive inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR), with IC50s of 27 and 25 nM, respectively. GSK1904529A shows poor activity (IC50>1 μM) in 45 other serine/threonine and tyrosine kinases. GSK1904529A exhibits anti-tumor activity.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	GSK1904529A
Formel vægt	851.96
Opløselighedsinformation	DMSO : 50 mg/mL (58.69 mM; Need ultrasonic)
Procent renhed	99.66%
Fysisk form	Solid
Farve	Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	851.96
CAS	1089283-49-7
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(C1=CC(C2=C(N3C=CC=CC3=N2)C4=NC(NC5=CC(CC)=C(C=C5OC)N6CCC(CC6)N7CCN(CC7)S(=O)(C)=O)=NC=C4)=CC=C1OC)NC8=C(C=CC=C8F)F
Renhedsgrad noter	Research
Molekylær formel	C₄₄H₄₇F₂N₉O₅S
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 1089283-49-7

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