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GSK1904529A, MedChemExpress

Artikelnummer. 16480377
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10 mg
50 mg
100 mg
Pakningsstørrelse:
50mg
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16480377 50 mg 50mg
16425016 100 mg -
16424028 10 mg -
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Artikelnummer. 16480377 Leverandør Medchem Express Leverandørnr. HY10524

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Beskrivelse

MedChemExpress GSK1904529A is a potent, selective, orally active, and ATP-competitive inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR), with IC50s of 27 and 25 nM, respectively. GSK1904529A shows poor activity (IC50>1 μM) in 45 other serine/threonine and tyrosine kinases. GSK1904529A exhibits anti-tumor activity.

GSK1904529A is a potent, selective, orally active, and ATP-competitive inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR), with IC50s of 27 and 25 nM, respectively. GSK1904529A shows poor activity (IC50>1 μM) in 45 other serine/threonine and tyrosine kinases. GSK1904529A exhibits anti-tumor activity.

Tekniske data

Kemisk navn eller materiale GSK1904529A
CAS 1089283-49-7
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C44H47F2N9O5S
Mængde 50 mg
Opløselighedsinformation DMSO : 50 mg/mL (58.69 mM; Need ultrasonic)
SMIL O=C(C1=CC(C2=C(N3C=CC=CC3=N2)C4=NC(NC5=CC(CC)=C(C=C5OC)N6CCC(CC6)N7CCN(CC7)S(=O)(C)=O)=NC=C4)=CC=C1OC)NC8=C(C=CC=C8F)F
Molekylvægt (g/mol) 851.96
Formel vægt 851.96
Procent renhed 99.66%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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