CAS RN 1073154-85-4

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Potent and selective FAK and Pyk2 inhibitor

Kemisk navn eller materiale	N-Methyl-4-[[4-[[[3-[methyl(methylsulfonyl)amino]-2-pyrazinyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]benzamide
Anbefalet opbevaring	Store at -20°C
CAS	1073154-85-4
Mål	Focal Adhesion Kinase Inhibitors
Renhed	0.98
Molekylær formel	C₂₀H₂₁F₃N₈O₃S

MedChemExpress Defactinib (VS-6063; PF-04554878) is a novel FAK inhibitor with potential antiangiogenic and antineoplastic activities.

Kemisk navn eller materiale	Defactinib
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	510.49
Opløselighedsinformation	DMSO : 50 mg/mL (97.95 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Procent renhed	98.41%
Fysisk form	Solid
Farve	Off-White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	510.49
CAS	1073154-85-4
Synonym	VS-6063 PF-04554878
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(NC)C1=CC=C(NC2=NC=C(C(F)(F)F)C(NCC3=NC=CN=C3N(C)S(=O)(C)=O)=N2)C=C1
Renhedsgrad noter	Research
Molekylær formel	C₂₀H₂₁F₃N₈O₃S
Til brug med (applikation)	Cancer-Kinase/protease