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Zamicastat, MedChemExpress

Artikelnummer. 16466767
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Artikelnummer. 16466767 Leverandør Medchem Express Leverandørnr. HY106004

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Beskrivelse

MedChemExpress Zamicastat (BIA 5-1058) is a dopamine β-hydroxylase (DBH) inhibitor and can cross the blood-brain barrier (BBB) to cause central as well as peripheral effects. Zamicastat is also a concentration-dependent dual P-gp and BCRP inhibitor with IC50 values of 73.8 μM and 17.0 μM, respectively. Zamicastat reduces high blood pressure.

Zamicastat (BIA 5-1058) is a dopamine β-hydroxylase (DBH) inhibitor and can cross the blood-brain barrier (BBB) to cause central as well as peripheral effects. Zamicastat is also a concentration-dependent dual P-gp and BCRP inhibitor with IC50 values of 73.8 μM and 17.0 μM, respectively. Zamicastat reduces high blood pressure.

Tekniske data

Kemisk navn eller materiale Zamicastat
CAS 1080028-80-3
Farve Off-White
Renhedsgrad noter Research
Molekylær formel C21H21F2N3OS
Mængde 5 mg
Synonym BIA 5-1058
Opløselighedsinformation DMSO : 150 mg/mL (373.63 mM; Need ultrasonic)
SMIL S=C1N([C@@H]2CC3=CC(F)=CC(F)=C3OC2)C(CCNCC4=CC=CC=C4)=CN1
Molekylvægt (g/mol) 401.47
Formel vægt 401.47
Procent renhed 95.36%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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