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WIKI4, MedChemExpress

Artikelnummer. 16453227
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Artikelnummer. 16453227 Leverandør Medchem Express Leverandørnr. HY16910

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MedChemExpress WIKI4 is a potent tankyrase inhibitor with an IC50 of 26 nM for TNKS2. WIKI4 potently inhibits Wnt/β-catenin signaling and that its half-maximal response dose is 75 nM. WIKI4 mediates its effects on Wnt/β-catenin signaling by inhibiting the enzymatic activity of TNKS2. WIKI4 is cytotoxic to SCLC cells with an IC50 value of 0.02 μM.

WIKI4 is a potent tankyrase inhibitor with an IC50 of 26 nM for TNKS2. WIKI4 potently inhibits Wnt/β-catenin signaling and that its half-maximal response dose is 75 nM. WIKI4 mediates its effects on Wnt/β-catenin signaling by inhibiting the enzymatic activity of TNKS2. WIKI4 is cytotoxic to SCLC cells with an IC50 value of 0.02 μM.

Tekniske data

Kemisk navn eller materiale WIKI4
CAS 838818-26-1
Farve Tan
Renhedsgrad noter Research
Molekylær formel C29H23N5O3S
Mængde 50 mg
Opløselighedsinformation DMSO : 6.8 mg/mL (13.04 mM; Need ultrasonic and warming)
SMIL O=C1N(CCCSC2=NN=C(C3=CC=NC=C3)N2C4=CC=C(OC)C=C4)C(C5=CC=CC6=CC=CC1=C56)=O
Molekylvægt (g/mol) 521.59
Formel vægt 521.59
Procent renhed 99.93%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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