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Vactosertib, MedChemExpress

Artikelnummer. 16480428
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16480428 5 mg
16447968 10 mg
16447756 100 mg
16443897 50 mg
16423716 25 mg
16400336 2 mg
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Artikelnummer. 16480428 Leverandør Medchem Express Leverandørnr. HY19928

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Beskrivelse

MedChemExpress Vactosertib (EW-7197) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib has potently antimetastatic activity and anticancer effect.

Vactosertib (EW-7197) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib has potently antimetastatic activity and anticancer effect.

Tekniske data

Kemisk navn eller materiale Vactosertib
CAS 1352608-82-2
Farve Light Yellow
Renhedsgrad noter Research
Molekylær formel C22H18FN7
Mængde 5 mg
Synonym EW-7197 TEW-7197
Opløselighedsinformation DMSO : 100 mg/mL (250.36 mM; Need ultrasonic)
SMIL CC1=CC=CC(C2=C(C3=CN4C(C=C3)=NC=N4)NC(CNC5=CC=CC=C5F)=N2)=N1
Molekylvægt (g/mol) 399.42
Formel vægt 399.42
Procent renhed 98.27%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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