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Vactosertib Hydrochloride, MedChemExpress

Artikelnummer. 16490428
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16490428 5 mg
16457968 10 mg
16457756 100 mg
16453897 50 mg
16433716 25 mg
16410336 2 mg
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Artikelnummer. 16490428 Leverandør Medchem Express Leverandørnr. HY19928A

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Beskrivelse

MedChemExpress Vactosertib Hydrochloride (EW-7197 Hydrochloride) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib Hydrochloride has potently antimetastatic activity and anticancer effect.

Vactosertib Hydrochloride (EW-7197 Hydrochloride) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib Hydrochloride has potently antimetastatic activity and anticancer effect.

Tekniske data

Kemisk navn eller materiale Vactosertib Hydrochloride
CAS 1352610-25-3
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C22H19ClFN7
Mængde 5 mg
Synonym EW-7197 HydrochlorideTEW-7197 Hydrochloride
Opløselighedsinformation H2O : 50 mg/mL (114.71 mM; Need ultrasonic) ∣DMSO : 50 mg/mL (114.71 mM; Need ultrasonic)
SMIL CC1=CC=CC(C2=C(C3=CN4C(C=C3)=NC=N4)NC(CNC5=CC=CC=C5F)=N2)=N1.Cl
Molekylvægt (g/mol) 435.88
Formel vægt 435.88
Procent renhed 96.24%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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