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Invitrogen™ Transferrin Receptor Monoclonal Antibody (H68.4)
GREENER_CHOICE

Mouse Monoclonal Antibody

3905.00 DKK - 8280.00 DKK

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Tekniske data

Antigen Transferrin Receptor
Klon H68.4
Koncentration 0.5 mg/mL
Indhold og opbevaring -20°C
Applikationer ELISA, Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation, Western Blot, Immunocytochemistry
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Produkter 2
Produktkode Brand Mængde Pris Antal & tilgængelighed  
Produktkode Brand Mængde Pris Antal & tilgængelighed  
10372703
GREENER_CHOICE
Dokumentvisning Kampagnedetaljer
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Invitrogen™
136800 		100 μg
3905.00 DKK
100µg
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10516083
Dokumentvisning
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Invitrogen™
136890 		500 μg
8280.00 DKK
500µg
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Beskrivelse

Beskrivelse

H68.4 is specific to residues 3-28 of the human transferrin receptor (TfR) tail.

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
Tekniske data

Tekniske data

Transferrin Receptor
0.5 mg/mL
ELISA, Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation, Western Blot, Immunocytochemistry
Unconjugated
Mouse
RUO
PBS with 0.1% sodium azide; pH 7.4
P02786, Q07891, Q62351, Q90997, Q99376
100689395, 22042, 396191, 64678, 7037
Recombinant human transferrin receptor.
Antibody
H68.4
-20°C
Monoclonal
Liquid
IgG1
Chicken, Hamster, Human, Mouse, Rat
TFRC
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
TFRC
Primary
Affinity chromatography
Videoer
SDS
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