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  6. Invitrogen™ Transferrin Receptor Monoclonal Antibody (H68.4) 

Invitrogen™ Transferrin Receptor Monoclonal Antibody (H68.4)
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Artikelnummer. 10372703
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Mængde:
100 μg
500 μg
Pakningsstørrelse:
Hver
Artikelnummer. Mængde unitSize
10372703 100 μg Hver
10516083 500 μg Hver
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Artikelnummer. 10372703

Brand: Invitrogen™ 136800

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Beskrivelse

Mouse Monoclonal Antibody

H68.4 is specific to residues 3-28 of the human transferrin receptor (TfR) tail.

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen Transferrin Receptor
Applikationer ELISA, Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation, Western Blot, Immunocytochemistry
Klassifikation Monoclonal
Klon H68.4
Koncentration 0.5 mg/mL
Konjugeret Unconjugated
Formulering PBS with 0.1% sodium azide; pH 7.4
Gene TFRC
Genadgangsnr. P02786, Q07891, Q62351, Q90997, Q99376
Gene Alias 2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Gensymboler TFRC
Værtsarter Mouse
Immunogen Recombinant human transferrin receptor.
Oprensningsmetode Affinity chromatography
Mængde 100 μg
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 100689395, 22042, 396191, 64678, 7037
Målarter Human, Mouse, Rat, Hamster, Chicken
Indhold og opbevaring -20°C
Produkttype Antibody
Form Liquid
Isotype IgG1
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