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Tolfenamic acid, 99+%, Thermo Scientific™

NSAID that activates calcium-activated potassium channels

Brand:  Thermo Scientific Alfa Aesar J61256.09


Mængde 10g

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Regulatorisk: Dette produkt falder ind under Lov om kemiske stoffer og produkter - lovbekendtgørelse nr. 1755 af 22. december 2006. Hvis det er relevant, skal kunden fremskaffe en licens før levering.

Produktkode 15473869

  • 1119.42 DKK / 10g

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Beskrivelse

Beskrivelse

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
Tolfenamic acid is a non-steroidal anti-inflammatory agent. It interferes with synthesis of β-amyloid precursor protein, and thus Aβ peptides, by promoting degradation of an essential transcription factor. It inhibits fMLP- and A23187-induced Ca2+ influx in human PMNL with an IC50 value of approximately 20 µM.

Solubility
Soluble in water (slightly), acetone (∼10 mg/ml), DMSO (52 mg/ml at 25°C), methanol (∼10 mg/ml) and ethanol (50 mg/ml).

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
TRUSTED_SUSTAINABILITY
Tekniske data

Kemiske identifikatorer

13710-19-5
261.705
YEZNLOUZAIOMLT-UHFFFAOYSA-N
610479
2-(3-chloro-2-methylanilino)benzoic acid
C14H12ClNO2
MFCD00133865
tolfenamic acid, clotam, n-3-chloro-2-methylphenyl anthranilic acid, 2-3-chloro-2-methylphenyl amino benzoic acid, tolfedine, acido tolfenamico, acide tolfenamique, acidum tolfenamicum, tolfine, n-2-methyl-3-chlorophenyl anthranilic acid
CHEBI:32243
CC1=C(C=CC=C1Cl)NC2=CC=CC=C2C(=O)O

Tekniske data

Tolfenamic acid
C14H12ClNO2
10g
14,9513
Soluble in water (slightly),acetone (∽10mg/ml),DMSO (52mg/ml at 25°C),methanol (∽10mg/ml) and ethanol (50mg/ml).
CC1=C(C=CC=C1Cl)NC2=CC=CC=C2C(=O)O
261.705
CHEBI:32243
≥99%
13710-19-5
MFCD00133865
UN2811
tolfenamic acid, clotam, n-3-chloro-2-methylphenyl anthranilic acid, 2-3-chloro-2-methylphenyl amino benzoic acid, tolfedine, acido tolfenamico, acide tolfenamique, acidum tolfenamicum, tolfine, n-2-methyl-3-chlorophenyl anthranilic acid
YEZNLOUZAIOMLT-UHFFFAOYSA-N
2-(3-chloro-2-methylanilino)benzoic acid
610479
261.7
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Produktidentifikator
  • Tolfenamic acid

Signalord
  • Fare

Farekategori
  • Akut toksicitet Kategori 3

Faresætning
  • H301-Giftig ved indtagelse.

Sikkerhedssætning
  • P264-Vask grundigt efter brug.
  • P301+P310-I TILFÆLDE AF INDTAGELSE: Ring omgående til en GIFTINFORMATION/læge

Supplerende oplysninger
  • MIXTURE LIST-Contain: Tolfenamic acid

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