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Tofogliflozin (hydrate), MedChemExpress

MedChemExpress Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific sodium/glucose cotransporter 2 (SGLT2) inhibitor with an IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2. Tofogliflozin partially inhibits high glucose-induced reactive oxyen species (ROS) generation in tubular cells.

1148.12 DKK - 6183.73 DKK

Specifications

Chemical Name or Material	Tofogliflozin (hydrate)
CAS	1201913-82-7
Color	White
Purity Grade Notes	Research
Molecular Formula	C₂₂H₂₈O₇

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16485668 View Documents missing translation for 'viewProductCertificates'	Medchem Express HY-13413	10 mg	1832.96 DKK 10mg View alternative products Save Up to »		Please sign in to purchase this item. Need a web account? Register with us today!

16438367 View Documents missing translation for 'viewProductCertificates'	Medchem Express HY-13413	5 mg	1148.12 DKK 5mg View alternative products Save Up to »		Please sign in to purchase this item. Need a web account? Register with us today!

16431837 View Documents missing translation for 'viewProductCertificates'	Medchem Express HY-13413	50 mg	6183.73 DKK 50mg View alternative products Save Up to »		Please sign in to purchase this item. Need a web account? Register with us today!

Description

Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific sodium/glucose cotransporter 2 (SGLT2) inhibitor with an IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2. Tofogliflozin partially inhibits high glucose-induced reactive oxyen species (ROS) generation in tubular cells.

Specifications

Chemical Name or Material	Tofogliflozin (hydrate)
Color	White
Molecular Formula	C₂₂H₂₈O₇
Solubility Information	DMSO : ≥ 100 mg/mL (247.25 mM) ∣H2O : 0.33 mg/mL (0.82 mM; Need ultrasonic)
Molecular Weight (g/mol)	404.45
Percent Purity	98.73%
Physical Form	Solid

CAS	1201913-82-7
Purity Grade Notes	Research
Synonym	CSG-452 hydrate
SMILES	O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@]21OCC3=C2C=C(CC4=CC=C(CC)C=C4)C=C3.O
Formula Weight	404.45
Grade	Research
For Use With (Application)	Metabolism-sugar/lipid metabolism

Safety and Handling

H302∣H315∣H319∣H335

missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

Research purposes only

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Tofogliflozin (hydrate), MedChemExpress

Specifications

Description

Specifications

Safety and Handling

Documents