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Toceranib, MedChemExpress

Artikelnummer. 16493818
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16493818 10 mg
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Artikelnummer. 16493818 Leverandør Medchem Express Leverandørnr. HY10330

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MedChemExpress Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with Kis of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively. Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors.

Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with Kis of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively. Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors.

Tekniske data

Kemisk navn eller materiale Toceranib
CAS 356068-94-5
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C22H25FN4O2
Mængde 10 mg
Synonym SU11654 PHA 291639E
Opløselighedsinformation DMSO : 2.5 mg/mL (6.31 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
SMIL O=C(NCCN1CCCC1)C2=C(NC(/C=C3C(NC4=C\3C=C(C=C4)F)=O)=C2C)C
Molekylvægt (g/mol) 396.46
Formel vægt 396.46
Procent renhed 96.86%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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