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TAK-960, MedChemExpress

Artikelnummer. 16488917
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Mængde:
5 mg
10 mg
50 mg
100 mg
Pakningsstørrelse:
50mg
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Artikelnummer. 16488917 Leverandør Medchem Express Leverandørnr. HY15160

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Beskrivelse

MedChemExpress TAK-960 is an orally available, selective inhibitor of polo-like kinase 1 (PLK1), with an IC50 of 0.8 nM. TAK-960 also shows inhibitory activities against PLK2 and PLK3, with IC50s of 16.9 and 50.2 nM, respectively. TAK-960 inhibits proliferation of multiple cancer cell lines and exhibits significant efficacy against multiple tumor xenografts.

TAK-960 is an orally available, selective inhibitor of polo-like kinase 1 (PLK1), with an IC50 of 0.8 nM. TAK-960 also shows inhibitory activities against PLK2 and PLK3, with IC50s of 16.9 and 50.2 nM, respectively. TAK-960 inhibits proliferation of multiple cancer cell lines and exhibits significant efficacy against multiple tumor xenografts.

Tekniske data

Kemisk navn eller materiale TAK-960
CAS 1137868-52-0
Farve White
Renhedsgrad noter Research
Molekylær formel C27H34F3N7O3
Mængde 5 mg
Opløselighedsinformation DMSO : 16.67 mg/mL (29.68 mM; ultrasonic and warming and heat to 60°C)
SMIL O=C(NC1CCN(C)CC1)C2=CC(OC)=C(NC3=NC=C(N4C)C(N(C5CCCC5)CC(F)(F)C4=O)=N3)C=C2F
Molekylvægt (g/mol) 561.6
Formel vægt 561.6
Procent renhed 95.44%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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